ASPG Menu
search

American Scientific Publishing Group

verified Journal

Metaheuristic Optimization Review

ISSN
Online: 3066-280X
Frequency

Continuous publication

Publication Model

Open access journal. All articles are freely available online with no APC.

Metaheuristic Optimization Review
Review Article

Volume 6Issue 2PP: 14–18 • 2026

The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review

Mona Yassen 1*
1Computer Science and Intelligent Systems Research Center, Blacksburg 24060, Virginia, USA
* Corresponding Author.
Received: January 17, 2026 Revised: February 15, 2026 Accepted: April 15, 2026

Abstract

Generative models, including GANs, VAEs, and autoregressive models, have drastically improved neurological and psychological analyses. They allow for the formation of complex data representations that imitate cognitive processes in a human brain and thus help to understand the workings of the brain and mental diseases. Thus, GANs trained with adversarial mechanisms can synthesize nearly photorealistic fake samples, which can mimic neurological disorders or assess the effectiveness of treatment. VAEs are known to give a formidably well founded method of learning the hidden representations of psychological states, therefore allowing researchers to study the potential causes of mental health problems. Autoregressive models, in contrast, are most applicable in time series data, which is highly important when the neurological signal or behavior under investigation needs to be studied over time. This broad survey discusses the assets and liabilities of these generative approaches, emphasizing their usability in simulating elaborate psychological processes and deploying evidence-based observations to understand the assessment and therapy of mental disorders. Therefore, this work aims to reveal the significant connections between these methodologies and their further potential for investigating human cognition and behavior through the coordinated usage of highly effective computational methods.

Keywords

Generative Models GANs Autoregressive Models Neuroscience Mental Health Disorders

References

[1] R. Onciul, C.-I. Tataru, A. V. Dumitru, C. Crivoi, M. Serban, R.-A. Covache-Busuioc, M. P. Radoi, and C. Toader, “Artificial intelligence and neuroscience: Transformative synergies in brain research and clinical applications,” Journal of Clinical Medicine, vol. 14, no. 2, p. 550, 2025.

[2] M. Joshi, B. Kapila, N. Rani, and N. A. Sagar, “History, fundamentals, and evolution of artificial intelligence,” in Artificial Intelligence Interventions in Agriculture, Food and Health Sectors, N. A. Sagar, S. Agarwal, S. Sharma, V. Singh, and A. R. Jambrak, Eds. Academic Press, 2026, pp. 1–21.

[3] E. Gkintoni, H. Antonopoulou, A. Sortwell, and C. Halkiopoulos, “Challenging cognitive load theory: The role of educational neuroscience and artificial intelligence in redefining learning efficacy,” Brain Sciences, vol. 15, no. 2, p. 203, 2025.

[4] S. Bengesi, H. El-Sayed, M. K. Sarker, Y. Houkpati, J. Irungu, and T. Oladunni, “Advancements in generative ai: A comprehensive review of gans, gpt, autoencoders, diffusion model, and transformers,” IEEE Access, vol. 12, pp. 69 812–69 837, 2024.

[5] J. Cao, J. Miao, H. Tao, Y. Wang, J. Wu, Z. Wang, and X. Wu, “Generative models for time series anomaly detection: A survey,” IEEE Transactions on Artificial Intelligence, vol. 7, no. 4, pp. 2253–2275, 2026.

[6] S. S. Sengar, A. B. Hasan, S. Kumar, and F. Carroll, “Generative artificial intelligence: A systematic review and applications,” Multimedia Tools and Applications, vol. 84, no. 21, pp. 23 661–23 700, 2025.

[7] M. B. Rocha and R. A. Krohling, “Vae-gna: A variational autoencoder with gaussian neurons in the latent space and attention mechanisms,” Knowledge and Information Systems, vol. 66, no. 10, pp. 6415–6437, 2024.

[8] M. B. Oluwagbenro, “Generative ai: Definition, concepts, applications, and future prospects,” TechRxiv, 2024.

[9] Z. Ahmad, Z. u. A. Jaffri, M. Chen, and S. Bao, “Understanding gans: Fundamentals, variants, training challenges, applications, and open problems,” Multimedia Tools and Applications, vol. 84, no. 12, pp. 10 347– 10 423, 2025.

[10] S. Bond-Taylor, A. Leach, Y. Long, and C. G.Willcocks, “Deep generative modelling: A comparative review of vaes, gans, normalizing flows, energy-based and autoregressive models,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 44, no. 11, pp. 7327–7347, 2022.

[11] M. Du, H. Jing, Y. Ma, and N. Zheng, “Hierarchical causality network: Find the effective connectivity in visual cortex,” in IFIP International Conference on Artificial Intelligence Applications and Innovations. Springer, 2022, pp. 407–419.

[12] S. M. Bradley, F. L. Hanley, B. W. Duncan, R. W. Jennings, J. A. Jester, M. R. Harrison, and E. D. Verrier, “Fetal cardiac bypass alters regional blood flows, arterial blood gases, and hemodynamics in sheep,” American Journal of Physiology-Heart and Circulatory Physiology, vol. 263, no. 3, pp. H919–H928, 1992.

[13] S. Martinez-Conde, “Fixational eye movements in normal and pathological vision,” in Visual Perception, ser. Progress in Brain Research, S. Martinez-Conde, S. L. Macknik, L. M. Martinez, J.-M. Alonso, and P. U. Tse, Eds. Elsevier, 2006, vol. 154, pp. 151–176.

[14] D. Helen and N. V. Suresh, “Generative ai in healthcare: Opportunities, challenges, and future perspectives,” in Revolutionizing the Healthcare Sector with AI. IGI Global Scientific Publishing, 2024, pp. 79–90.

[15] S. Garg, A. Schneider, A. Raj, K. Rasul, Y. Nevmyvaka, S. Gopal, A. Dhurandhar, G. Cecchi, and I. Rish, “Deep generative sampling in the dual divergence space: A data-efficient & interpretative approach for generative ai,” arXiv Preprint arXiv:2404.07377, 2024.

Cite This Article

Choose your preferred format

format_quote
Yassen, Mona . "The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review." Metaheuristic Optimization Review, vol. Volume 6, no. Issue 2, 2026, pp. 14–18. DOI: https://doi.org/10.54216/MOR.060202
Yassen, M. (2026). The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review. Metaheuristic Optimization Review, Volume 6(Issue 2), 14–18. DOI: https://doi.org/10.54216/MOR.060202
Yassen, Mona . "The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review." Metaheuristic Optimization Review Volume 6, no. Issue 2 (2026): 14–18. DOI: https://doi.org/10.54216/MOR.060202
Yassen, M. (2026) 'The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review', Metaheuristic Optimization Review, Volume 6(Issue 2), pp. 14–18. DOI: https://doi.org/10.54216/MOR.060202
Yassen M. The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review. Metaheuristic Optimization Review. 2026;Volume 6(Issue 2):14–18. DOI: https://doi.org/10.54216/MOR.060202
M. Yassen, "The Role of GANs, VAEs, and Autoregressive Models in Neurological and Psychological Research: A Comprehensive Review," Metaheuristic Optimization Review, vol. Volume 6, no. Issue 2, pp. 14–18, 2026. DOI: https://doi.org/10.54216/MOR.060202
Digital Archive Ready