Journal of Intelligent Systems and Internet of Things JISIoT 2690-6791 2769-786X 10.54216/JISIoT https://www.americaspg.com/journals/show/3053 2019 2019 Research Scholar, Department of Electronics and Communication Engineering, Annamalai University, Annamalai Nagar, India B. B. Assistant Professor, Department of Electronics and Communication Engineering, Annamalai University, Annamalai Nagar, India E. Gnanamanoharan Professor Department of Electronics and Communication Engineering, S.R.K.R. Engineering College, Bhimavaram, India N. Udaya Kumar Brain tumor is an abnormal development of brain cells that, if left untreated, can have severe consequences. Brain tumour semantic segmentation is the process of determining and distinguishing the impacted brain regions, which is essential for accurate diagnosis, treatment planning, as well as surveillance of the tumor's development over time. This paper presents a model for identifying and segmenting brain tumor using Unet architecture with the optimization of hyper parameters using the Moth Flame Optimization (MFO) algorithm. Due to its capacity to collect spatial information, the Unit architecture is a common choice for picture segmentation tasks. The MFO algorithm is an optimization technique that draws inspiration and replicates from the behavior of moths. Both techniques are developed to improve efficiency. The performance of the model has increased using the MFO method, which led to improved segmentation results. Based on comparative analysis report, the proposed model shows a percentage improvement of approximately 65.16% in MSE, 28.87% in PSNR, and 40.30% in Tversky compared to the Unet and Unet++ models. This method has demonstrated good results in identifying and segmenting brain tumors, which can be helpful in the early identification and treatment of brain tumor. 2024 2024 334 346 10.54216/JISIoT.130226 https://www.americaspg.com/articleinfo/18/show/3053