International Journal of Neutrosophic Science IJNS 2690-6805 2692-6148 10.54216/IJNS https://www.americaspg.com/journals/show/1067 2020 2020 American University in the Emirates, UAE Abedallah Zaid .. Department of Mathematical Sciences, Faculty of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia Sundus Naji AL AL-Aziz The goal of this paper studying the influence of physical exercise (PE) on the human body. Physical exercise plays a vital role in the nervous system and respiratory due it has significant importance. The PE present a benefit in all functions in the body human. But if PE is not regular, it presents a high risk in humans, and humans are not safe when practices it. The impact of PE has many criteria and sub-criteria, which is complex and conflict criteria. So, the multi-criteria decision-making method is present for overcoming this problem. This problem contains incomplete and vague information. So, the neutrosophic sets are used for overcoming uncertainty. The Decision-making trial and evaluation laboratory (DEMATEL) method is a powerful tool for the present the importance and influence criteria on others. So DEMATEL integrated with neutrosophic sets for analyzing and influence regular PE in body human-like nervous systems. An illustrative example was conducted to show the outcome of this method.    2022 2022 111 124 10.54216/IJNS.1803010 https://www.americaspg.com/articleinfo/21/show/1067