Volume 17 , Issue 2 , PP: 360-368, 2025 | Cite this article as | XML | Html | PDF | Full Length Article
Taha Y. Abdulqader 1 * , Kifaa Hadi Thanoon 2 , Shatha A. Baker 3
Doi: https://doi.org/10.54216/JISIoT.170223
When using mammography to diagnose breast cancer, segmenting medical scans is a crucial step. Accurate segmentation facilitates early diagnosis, which in turn makes it possible to administer individualized treatment plans, ultimately improving patient outcomes. However, for these Deep Learning (DL) models to be trained efficiently and perform optimally, they require access to large datasets. The lack of sufficient photographs in many publicly available datasets to adequately train deep learning models is a common flaw. Therefore, this work aims to examine the effects of various affine data augmentations on the Dice Score of a U-NET model utilizing a recently released public dataset of Contrast-Enhanced Spectral Mammography (CESM) images. The collection consists of 1003 CESM images and matching segmentation masks made by a certified radiologist. Modifying certain model parameters on the CESM dataset and investigating the impact of single and combination data augmentations on the model's overall performance are the objectives of the study. Images that were moved in the x-direction and sheared vertically were used to train the best-performing model. On the test set, the model's Dice Score was 56.6%, which was 9% better than the baseline result and showed how crucial data augmentation is when working with small datasets.
Deep Learning , Contrast-Enhanced Spectral Mammography , Mammograms , U-NET
[1] J. A. P. Catarino, “End-to-end deep learning pipeline for breast cancer detection, segmentation and classification in contrast-enhanced spectral mammography,” M.S. thesis, Univ. de Lisboa (Portugal), 2022.
[2] L. Caselles, C. Jailin, and S. Muller, “Data augmentation for breast cancer mass segmentation,” in Proc. Int. Conf. Medical Imaging and Computer-Aided Diagnosis, Singapore: Springer, Mar. 2021, pp. 228–237.
[3] F. Z. Nakach, A. Idri, and A. Tsirikoglou, “Fusion of real and synthetic subtracted contrast-enhanced mammograms for enhanced tumor detection,” in Proc. 2024 Int. Conf. Machine Learning and Applications (ICMLA), pp. 1736–1740, Dec. 2024.
[4] Carriero, L. Groenhoff, E. Vologina, P. Basile, and M. Albera, “Deep learning in breast cancer imaging: State of the art and recent advancements in early 2024,” Diagnostics, vol. 14, no. 8, p. 848, 2024.
[5] Khorshidifar, G. Mostaghel, K. Dastvareh, Y. Ahmadyar, and R. Samimi, “Generating pseudo-subtracted image in dual-energy contrast-enhanced spectral mammography using transfer learning,” 2025.
[6] Liu, T. Huang, Y. He, H. Chen, Z. Wu, and Y. Yang, “Semi-supervised medical lesion image segmentation based on a contrast-guided diffusion model,” IEEE Trans. Radiat. Plasma Med. Sci., 2025.
[7] M. Sakaida, T. Yoshimura, M. Tang, S. Ichikawa, H. Sugimori, K. Hirata, and K. Kudo, “The effectiveness of semi-supervised learning techniques in identifying calcifications in X-ray mammography and the impact of different classification probabilities,” Appl. Sci., vol. 14, no. 14, p. 5968, 2024.
[8] M. Alshahrani, N. Alzahrani, and A. A. Alshahrani, “A Review of Machine Learning Techniques for Breast Cancer Diagnosis,” Journal of Healthcare Engineering, vol. 2023, pp. 1-12, 2023.
[9] R. Khan, F. Khan, and S. Hussain, “Deep Learning for Medical Image Analysis: A Review,” Journal of Medical Systems, vol. 46, no. 2, pp. 1-15, 2022.
[10] J. Smith, K. Johnson, and L. Brown, “Enhancing Image Segmentation with Transfer Learning Techniques,” Computers in Biology and Medicine, vol. 145, p. 105293, 2022.
[11] Patel, R. Gupta, and M. Verma, “Artificial Intelligence in Radiology: Current Applications and Future Directions,” Radiology Research and Practice, vol. 2024, pp. 1-10, 2024.
[12] N. Marwah, V. K. Singh, G. S. Kashyap, and S. Wazir, “An analysis of the robustness of UAV agriculture field coverage using multi-agent reinforcement learning,” Int. J. Inf. Technol., vol. 15, no. 4, pp. 2317–2327, May 2023.
[13] H. Habib, G. S. Kashyap, N. Tabassum, and T. Nafis, “Stock Price Prediction Using Artificial Intelligence Based on LSTM– Deep Learning Model,” in Artificial Intelligence & Blockchain in Cyber Physical Systems: Technologies & Applications, CRC Press, 2023, pp. 93–99.
[14] Chaix, G. Delamon, A. Guillemassé, B. Brouard, and J. E. Bibault, “Psychological distress during the COVID-19 pandemic in France: A national assessment of at-risk populations,” Gen. Psychiatry, vol. 33, no. 6, p. 100349, Nov. 2020.
[15] M. T. Shaban, C. Baur, N. Navab, and S. Albarqouni, “Staingan: Stain style transfer for digital histological images,” in Proceedings - International Symposium on Biomedical Imaging, IEEE Computer Society, Apr. 2019, pp. 953–956.
[16] H. Muhammad et al., “Unsupervised subtyping of cholangiocarcinoma using a deep clustering convolutional autoencoder,” in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer Science and Business Media Deutschland GmbH, 2019, pp. 604–612.
[17] R. H. J. M. Kurvers et al., “How to detect high-performing individuals and groups: Decision similarity predicts accuracy,” Sci. Adv., vol. 5, no. 11, Nov. 2019.
[18] K. Zormpas-Petridis, R. Noguera, D. K. Ivankovic, I. Roxanis, Y. Jamin, and Y. Yuan, “SuperHistopath: A Deep Learning Pipeline for Mapping Tumor Heterogeneity on Low-Resolution Whole-Slide Digital Histopathology Images,” Front. Oncol., vol. 10, p. 3052, Jan. 2021.
[19] G. Atteia et al., “Adaptive Dynamic Dipper Throated Optimization for Feature Selection in Medical Data,” Comput. Mater. Contin., vol. 75, no. 1, pp. 1883–1900, Feb. 2023.
[20] J. G. Precious and S. Selvan, “Detection of Abnormalities in Ultrasound Images Using Texture and Shape Features,” in Proceedings of the 2018 International Conference on Current Trends towards Converging Technologies, ICCTCT 2018, Institute of Electrical and Electronics Engineers Inc., Nov. 2018.
[21] R. H. J. M. Kurvers, S. M. Herzog, R. Hertwig, J. Krause, and M. Wolf, “Pooling decisions decreases variation in response bias and accuracy,” iScience, vol. 24, no. 7, p. 102740, 2021.
[22] R. Mishra, O. Daescu, P. Leavey, D. Rakheja, and A. Sengupta, “Convolutional neural network for histopathological analysis of osteosarcoma,” in Journal of Computational Biology, Mary Ann Liebert, Inc. 140 Huguenot Street, 3rd Floor New Rochelle, NY 10801 USA, Mar. 2018, pp. 313–325.
[23] J. Z. Cheng et al., “Computer-Aided Diagnosis with Deep Learning Architecture: Applications to Breast Lesions in US Images and Pulmonary Nodules in CT Scans,” Sci. Rep., vol. 6, no. 1, pp. 1–13, Apr. 2016.
[24] Carmichael et al., “JOINT AND INDIVIDUAL ANALYSIS OF BREAST CANCER HISTOLOGIC IMAGES AND GENOMIC COVARIATES,” Ann. Appl. Stat., vol. 15, no. 4, pp. 1697–1722, Dec. 2021.
[25] A. Adegun, S. Viriri, and R. O. Ogundokun, “Deep Learning Approach for Medical Image Analysis,” Comput. Intell. Neurosci., vol. 2021, 2021.