Journal of Artificial Intelligence and Metaheuristics JAIM 2833-5597 10.54216/JAIM https://www.americaspg.com/journals/show/4113 2022 2022 Department of System Programming, South Ural State University, 454080 Chelyabinsk, Russia Hussein Hussein Department of System Programming, South Ural State University, 454080 Chelyabinsk, Russia Mostafa Abotaleb A brain stroke represents a deadly health condition that emerges from poor blood flow to the brain. Brain tissue affected by a stroke will completely cease regular operations. Immediate detection of a brain stroke leads to better treatment success. Images from computed tomography (CT) provide a quick diagnosis of stroke. But time is passing quickly as the physicians examine each brain CT scan. This situation could cause therapy to be delayed and mistakes to be made. Thus, we focused on using a practical artificial intelligence algorithm for stroke detection. This paper proposes several deep neural network models, such as DenseNet121, ResNet50, Xception, and EfficientNetV2S, for transfer learning to study the features of stroke lesions and achieve complete intelligent automatic detection by classifying CT images into two categories (stroke and normal). The dataset comprises 437 testing, 235 validation, and 1843 training photos. Using the same dataset, the experimental findings outperform all state-of-the-art. The optimal model utilizing the EfficientNetV2S model for transfer learning has an overall accuracy of 99.57% and the same value for precision and recall. 2025 2025 52 71 10.54216/JAIM.100103 https://www.americaspg.com/articleinfo/28/show/4113