International Journal of BIM and Engineering Science IJBES 2571-1075 10.54216/IJBES https://www.americaspg.com/journals/show/3326 2021 2021 Explainable AI for Automated Feature Extraction in Medical Image Segmentation Assistant Professor, School of Computer Science and IT, Jain (Deemed-to-be University), Bangalore, India N. N. Professor, Karpagam College of Engineering, Coimbatore, India M. Balakrishnan Assistant Professor, Dr.Mahalingam College of Engineering and Technology, Pollachi, India S. R. Indurekaa Professor & Head, Department of Master of Computer Applications, Rathinam Technical Campus, Coimbatore, India A. B. Arockia Christopher Automated feature extraction and segmentation of medical images are essential for accurate diagnostics, enabling the identification of relevant structures with minimal human intervention. This study introduces an Explainable AI (XAI) framework for automated feature extraction in medical image segmentation, aiming to enhance transparency in deep learning models used in medical imaging. The proposed framework uses a Convolutional Neural Network (CNN) with integrated attention mechanisms and layer-wise relevance propagation (LRP) to identify critical features while segmenting regions of interest. Testing on datasets of MRI brain scans and CT liver scans, the model achieved an accuracy of 94%, a Dice similarity coefficient (DSC) of 0.88, and an Intersection over Union (IoU) score of 0.83. These results outperform conventional CNN-based segmentation techniques by 10% on average, highlighting the framework's precision in identifying and segmenting intricate structures, including lesions and abnormalities. Additionally, the XAI components provide visual explanations of the segmentation process, enabling clinicians to understand which features influenced the model's decisions. This enhanced transparency is crucial for building trust in AI-driven medical solutions, ultimately facilitating their integration into clinical workflows. 2024 2024 10 18 10.54216/IJBES.090202 https://www.americaspg.com/articleinfo/22/show/3326