International Journal of Neutrosophic Science IJNS 2690-6805 2692-6148 10.54216/IJNS https://www.americaspg.com/journals/show/2554 2020 2020 Faculty of computers and Informatics, Zagazig University, Zagazig, 44519, Egypt Mahmoud Mahmoud Faculty of computers and Informatics, Zagazig University, Zagazig, 44519, Egypt Shereen .. Faculty of computers and Informatics, Zagazig University, Zagazig, 44519, Egypt Mahmoud M. Ismail Faculty of computers and Informatics, Zagazig University, Zagazig, 44519, Egypt Mohamed Emad Faculty of computers and Informatics, Zagazig University, Zagazig, 44519, Egypt Shimaa Said This paper proposed a framework for assessing the COVID-19 response in Egypt. COVID-19 plays a vital role in public health, and selecting the best response can decrease the impact of the disease. This study used the type 2 neutrosophic set as a framework for dealing with uncertainty. The assessment of the COVID-19 response has various conflicting criteria, so the concept of multi-criteria decision-making (MCDM) is used to deal with COVID-19 criteria. The MCDM methods are adopted with the type-2neutrosophic set—the typ-2 neutrosophic AHP-COPRAS-VIKOR methodology framework. The AHP is used to compute the criteria weights. The COPRAS and VIKOR methods are used to rank the alternatives. The case study in Egypt is conducted to show the best response to COVID-19. Five main criteria and nineteen sub-criteria are used in this paper. The methodologies employed in this paper aid as examples for future research endeavors, inspiring a continued dialogue on refining and advancing MCDM methodologies in public health disasters. 2024 2024 41 62 10.54216/IJNS.230404 https://www.americaspg.com/articleinfo/21/show/2554