International Journal of Advances in Applied Computational Intelligence IJAACI 2833-5600 10.54216/IJAACI https://www.americaspg.com/journals/show/2000 2022 2022 Deep Learning Framework of Convolutional Neural Network (CNN) and Attention CNN for Early Diagnosis of Alzheimer's Disease Faculty of Engineering, Ain Shams University, Cairo, Egypt Hoda K. Mohamed Faculty of Information Systems and Computer Science, October 6th University, Cairo, 12585, Egypt Ahmed Abdelhafeez Faculty of Information Systems and Computer Science, October 6th University, Cairo, 12585, Egypt Nariman A. Khalil One of the biggest killers in the industrialized world is Alzheimer's disease (AD). Although computer-aided techniques have shown promising outcomes in laboratory experiments, they have yet to be used in a clinical setting. Recently, deep neural networks have gained traction, particularly for image processing tasks. There has been a dramatic increase in the number of publications written on the topic of identifying AD using deep learning since 2017. It has been observed that deep networks are more efficient than standard machine learning methods for detecting AD. It remains difficult to identify AD because distinguishing between comparable brain signals during categorization needs an extremely discriminative depiction of features. This paper proposed a deep neural network method for prediction the AD. Low-level computer vision has been a hotspot for research into deep convolutional neural networks (CNNs). Studies often focus on enhancing performance through the use of very deep CNNs. Yet, as one goes deeper, the effect of the shallow layers on the deeper ones gradually diminishes. Prompted by reality. This paper compared with the CNN and attention CNN models. The proposed model applied in the AD dataset which contains 5121 images for the train set. The results showed the attention CNN model is better than the CNN model in accuracy, precision, recall, loss, and AUC. 2023 2023 08 17 10.54216/IJAACI.030201 https://www.americaspg.com/articleinfo/31/show/2000