Journal of Cybersecurity and Information Management JCIM 2690-6775 2769-7851 10.54216/JCIM https://www.americaspg.com/journals/show/17 2019 2019 Computer Science Department, Faculty of Computers and Artificial Intelligent, Beni-Suef University, Egypt Abdelrahim .. Faculty of Computers and Artificial Intelligent , Beni-Suef University, Egypt Hany S. Elnashar One of the most common health problems that correlated to serious complications is chronic kidney disease. Early detection and treatment can save it from progression. Machine learning is one tool that used historical data to improve future decision about prediction of chronic kidney disease.  The aim of this work is to compare the performance of six different models based on accuracy, sensitivity, precision, recall.  In this study, the experiments were conducted on 158 records downloaded from UCI repository. Six algorithms ( K-Nearest Neighbor, Naïve Bayes, Support Vector machine, Logistic Regression, Decision Tree, and Random Forest )  were implemented on data after preprocessing stage.   Evaluation of models resulted in Naïve Bayes and Random Forest accuracy 100%, Sensitivity 100%, Specificity 100%, precision 100 %, Recall 100% respectively. It is concluded that Naïve Bayes and Random Forest are better than other models. 2020 2020 21 29 10.54216/JCIM.010104 https://www.americaspg.com/articleinfo/2/show/17