aspg-41-4417-1792222808 20261017074008 American Scientific Publishing Group admin@americaspg.com American Scientific Publishing Group Metaheuristic Optimization Review MOR 3066-280X 2026 6 2 Besnik Qehaja Faculty of Telecommunications, Technical University of Sofia, Sofia, Bulgaria Abdullahi Abdu Ibrahim Department of Electrical and Computer Engineering, Altinbas University, Istanbul 34218, Turkey Wireless signal applications in biomedical science have tremendously developed to improve people’s health care systems and contactless human sensing technologies. This review aims to focus on the current development of wireless microsystems, stressing the application of the wireless microsystem for precise physiological measurement without physical contact. Bio-signals transmitted through wireless telemetry systems help healthcare practitioners cover large numbers of patients continuously without repeated invasive interventions, improving the quality of care. RF systems and data acquisition techniques are critical for constructing wireless biomedical devices with low power consumption, especially in implantable applications. Moreover, depending on the advancements in microtechnology, sensors and actuators are compact and can be combined with communication electronics to produce complex healthchecking systems. The review also presents issues like signal distortion and data processing procedure requirements to obtain correct measurements in complicated surroundings. As technology advances in wireless communication systems, their usage in the health sectors advances, and the upcoming innovations should make healthcare better for the patients and efficient for the clinicians. In this vein, this paper posits wireless technologies as crucial to the advancement and contours of the future of personalized healthcare through monitoring and engagement. 2026 33 41 4417 https://creativecommons.org/licenses/by/4.0/ 10.54216/MOR.060205 https://americaspg.com/journal/41/article/4417 https://americaspg.com/storage/articles/manuscripts/01KVEWESMCGMB6PTPTWZ9R75QH.pdf