aspg-18-4144-1792025599 20261015005319 American Scientific Publishing Group admin@americaspg.com American Scientific Publishing Group Journal of Intelligent Systems and Internet of Things JISIoT 2769-786X 2690-6791 2025 17 2 Taha Y. Abdulqader Networks and Computer Software Techniques, Northern Technical University, Mosul, Iraq Kifaa Hadi Thanoon Networks and Computer Software Techniques, Northern Technical University, Mosul, Iraq Shatha A. 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mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:8.0pt; mso-para-margin-left:0in; line-height:107%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi; mso-ansi-language:TR;} When using mammography to diagnose breast cancer, segmenting medical scans is a crucial step. Accurate segmentation facilitates early diagnosis, which in turn makes it possible to administer individualized treatment plans, ultimately improving patient outcomes. However, for these Deep Learning (DL) models to be trained efficiently and perform optimally, they require access to large datasets. The lack of sufficient photographs in many publicly available datasets to adequately train deep learning models is a common flaw. Therefore, this work aims to examine the effects of various affine data augmentations on the Dice Score of a U-NET model utilizing a recently released public dataset of Contrast-Enhanced Spectral Mammography (CESM) images. The collection consists of 1003 CESM images and matching segmentation masks made by a certified radiologist. Modifying certain model parameters on the CESM dataset and investigating the impact of single and combination data augmentations on the model's overall performance are the objectives of the study. Images that were moved in the x-direction and sheared vertically were used to train the best-performing model. On the test set, the model's Dice Score was 56.6%, which was 9% better than the baseline result and showed how crucial data augmentation is when working with small datasets. 2025 360 368 4144 https://creativecommons.org/licenses/by/4.0/ 10.54216/JISIoT.170223 https://americaspg.com/journal/18/article/4144 https://americaspg.com/storage/11759415020.pdf